Applicability of saliva in the diagnosis of COVID-19: a review
| Autor: | Gustavo de Amorim Barbosa Cabral, Éverson de Andrade Lemos, Maria Helena Chaves de Vasconcelos Catão, José de Alencar Fernandes Neto |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Saliva Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 030106 microbiology MEDLINE Scopus Infection control Scientific literature World health lcsh:Social Sciences 03 medical and health sciences 0302 clinical medicine medicine Medical physics 030212 general & internal medicine lcsh:Science (General) General Environmental Science lcsh:LC8-6691 lcsh:Special aspects of education business.industry Gold standard (test) Coronavirus lcsh:H Research strategies General Earth and Planetary Sciences Infectious diseases business lcsh:Q1-390 |
| Zdroj: | Research, Society and Development, Vol 9, Iss 9 (2020) |
| ISSN: | 2525-3409 |
| Popis: | In 2020, the World Health Organization (WHO) classified COVID-19 as a global pandemic. Since then, there is a need for new methods to facilitate the diagnosis and control of this disease. Currently, reverse transcription followed by real-time polymerase chain reaction (rRT-PCR) of respiratory samples obtained by swabs represents the gold standard in the qualitative detection of Sars-CoV-2 infection. However, this type of collection has several disadvantages, making saliva a potential tool for the diagnosis of COVID-19. Thus, the aim of this study is to evaluate, through a systematic review of current scientific literature, the applicability of saliva for the diagnosis of COVID-19 in comparison to current methods. A search was carried out in MEDLINE, SciELO, Scopus and Web of Science databases, using descriptors, strategies and pre-established criteria by two independent evaluators, followed by a manual search in the references of articles selected for full reading. The research strategies identified 476 studies and 1 study was added through manual search. After analysis, 200 articles were excluded because they were duplicated among results found in databases. With the completion of the screening process, 12 articles were included in this review. It was concluded that it is necessary to produce new studies in order to obtain even more reliable and effective data about the use of saliva in the diagnosis of COVID-19. However, studies have shown that this material can be an excellent alternative sample for the detection of SARS-CoV-2. |
| Databáze: | OpenAIRE |
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