Corneal decompensation in mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. A clinicopathologic case report

Autor:	Donald R. Johns, D B Drachman, William R. Green, W J Stark, T S Chang
Rok vydání:	1994
Předmět:	Mitochondrial encephalomyopathy Adult Male Pathology medicine.medical_specialty Abnormal mitochondria Molecular Sequence Data Kearns-Sayre Syndrome Mitochondrion DNA Mitochondrial Polymerase Chain Reaction Kearns–Sayre syndrome Pathogenesis Corneal edema medicine Humans Descemet Membrane Corneal Decompensation Base Sequence business.industry Corneal Edema medicine.disease eye diseases Mitochondria Muscle Ophthalmology Blotting Southern Ophthalmoplegia plus sense organs business Gene Deletion Keratoplasty Penetrating
Zdroj:	Cornea. 13(3)
ISSN:	0277-3740
Popis:	The authors describe the clinical, molecular genetic, and pathologic findings of a patient with corneal decompensation associated with the mitochondrial ophthalmoplegia plus (Kearns-Sayre) syndrome. Ultrastructurally abnormal mitochondria were observed and possibly implicate this organelle in the pathogenesis of corneal edema.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17100b2f9ffe7178845108e1558d955d https://pubmed.ncbi.nlm.nih.gov/8033580 Zobrazit plný text záznamu