Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes
| Autor: | Francesco d'Amore, Lars C. Gormsen, Peter Kamper, Hans Beier Ommen, Jonas Juul Hansen |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Adverse outcomes medicine.medical_treatment Case Report Disease DISEASE 03 medical and health sciences 0302 clinical medicine HYPOTENSION hemic and lymphatic diseases Internal medicine medicine Classical Hodgkin lymphoma Chemotherapy lcsh:RC633-647.5 business.industry Complete remission lcsh:Diseases of the blood and blood-forming organs General Medicine CHEMOTHERAPY Hypothermia OF-THE-LITERATURE 030220 oncology & carcinogenesis Hodgkin lymphoma medicine.symptom business Autonomic neuropathy 030217 neurology & neurosurgery |
| Zdroj: | Case Reports in Hematology Hansen, J J, Beier Ommen, H, Gormsen, L C, d'Amore, F A & Hjørnet Kamper, P M 2018, ' Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes ', Case Reports in Hematology, vol. 2018, 3726593 . https://doi.org/10.1155/2018/3726593 Case Reports in Hematology, Vol 2018 (2018) |
| ISSN: | 2090-6579 2090-6560 |
| DOI: | 10.1155/2018/3726593 |
| Popis: | We report a case presenting with recurrent episodes of severe hypothermia preceding the diagnosis of Hodgkin lymphoma. The episodes of hypothermia were accompanied by other symptoms of autonomic dysfunction, mainly hypotension, which could be caused by autonomic neuropathy as part of a paraneoplastic syndrome. In comparison with previous reports describing an association between the presence of hypothermia and an adverse outcome, the present patient has responded well to lymphoma-specific treatment and is currently in an ongoing complete remission. Due to the peculiar cyclic pattern of the hypothermic episodes presented in this case, we hypothesize whether intermittent release of disease-related chemo- and cytokines could be a plausible pathogenetic explanation. |
| Databáze: | OpenAIRE |
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