Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study
| Autor: | Simon Nichols, Anna Kallvikbacka-Bennett, Richard Page, Fiona Nation, Lee Ingle, Toni Goodman, Sean Carroll, Andrew L. Clark, Stefan T. Birkett, Claire Taylor |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class medicine.medical_treatment 030204 cardiovascular system & hematology Carotid Intima-Media Thickness Coronary artery disease 03 medical and health sciences 0302 clinical medicine Oxygen Consumption medicine Natriuretic peptide Aerobic exercise Humans 030212 general & internal medicine Exercise Rehabilitation Framingham Risk Score Cardiac Rehabilitation business.industry VO2 max Cardiorespiratory fitness C640 Middle Aged medicine.disease Exercise Therapy Physical therapy Exercise Test Female Cardiology and Cardiovascular Medicine Heart rate reserve business |
| Zdroj: | International journal of cardiology. 305 |
| ISSN: | 1874-1754 0167-5273 |
| Popis: | Background\ud Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and explain why CR no longer improves patient survival in recent studies. We aimed to determine whether routine exercise-based CR increases V̇O2peak using gold-standard maximal cardiopulmonary exercise testing (CPET), and to quantify the exercise training stimulus which might be insufficient in patients undertaking CR.\ud \ud \ud Methods\ud We studied the effects of a routine, twice weekly, exercise-based CR programme for eight weeks (intervention group) compared with abstention from supervised exercise training (control group) in patients with coronary heart disease. The primary outcome was V̇O2peak measured using CPET. We also measured changes in body composition using dual X-ray absorptiometry, carotid intima-media thickness, hs-CRP and N-terminal pro B-type natriuretic peptide at baseline, 10 weeks and one year. We also calculated the Calibre 5-year all-cause mortality risk score.\ud \ud \ud Results\ud Seventy patients (age 63.1 SD10.0 years; BMI 29.2 SD4.0 kg·m−2; 86% male) were recruited (n = 48 intervention; n = 22 controls). The mean aerobic exercise training duration was 23 min per training session, and the mean exercise training intensity was 45.9% of heart rate reserve. V̇O2peak was 23·3 ml·kg-1·min−1 at baseline, and there were no changes in V̇O2peak between groups at any time point. The intervention had no effect on any of the secondary endpoints.\ud \ud Conclusion\ud Routine CR does not lead to an increase in V̇O2peak and is unlikely to improve long-term outcomes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect