Additional file 3 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers

Autor: Ballot, Elise, Galland, Loïck, Mananet, Hugo, Boidot, Romain, Arnould, Laurent, Desmoulins, Isabelle, Mayeur, Didier, Kaderbhai, Courèche, Ilie, Silvia, Hennequin, Audrey, Bergeron, Anthony, Derangère, Valentin, Ghiringhelli, François, Truntzer, Caroline, Ladoire, Sylvain
Rok vydání: 2022
DOI: 10.6084/m9.figshare.21602070.v1
Popis: Additional file 3: Supplemental figure 2 (S2): Distributions of HRD score and S3 proportion according to BRCA 1/2 mutational status considering the whole cohort (n = 928) or by breast cancer subtypes (standard pathological classification or PAM50 subtypes). A–B. Violin plots representing the distribution of HRD score (A) and signature 3 proportion (B) according to breast cancer standard pathological classification and BRCA 1/2 mutational status. *: Wilcoxon p-value < 0.05. C–D. Violin plots representing the distribution of HRD score (C) and signature 3 proportion (D) according to PAM50 subtypes and BRCA 1/2 mutational status. *: Wilcoxon p-value < 0.05. E–F. Violin plots representing the distribution of HRD (E) and signature 3 proportion (F) score according to BRCA 1/2 mutational status.
Databáze: OpenAIRE