Relationship between T-wave amplitude and oxygen pulse in guinea pigs in hyperbaric helium and hydrogen
| Autor: | Eugenia O. Aukhert, Susan R. Kayar, E. C. Parker |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Physiology Diving Guinea Pigs Oxygen pulse Analytical chemistry chemistry.chemical_element Hydrox Helium Models Biological Heliox Electrocardiography Oxygen Consumption Heart Rate Physiology (medical) Heart rate Animals Telemetry Air Pressure Atmospheric pressure Chemistry Pulse (signal processing) High Pressure Neurological Syndrome Anesthesia Breathing Regression Analysis Hydrogen |
| Zdroj: | Journal of Applied Physiology. 85:798-806 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/jappl.1998.85.3.798 |
| Popis: | Diving is known to induce a change in the amplitude of the T wave (ATw) of electrocardiograms, but it is unknown whether this is linked to a change in cardiovascular performance. We analyzed ATw in guinea pigs at 10–60 atm and 25–36°C, breathing 2% O2 in either helium (heliox; n = 10) or hydrogen (hydrox; n = 9) for 1 h at each pressure. Core temperature and electrocardiograms were detected by using implanted radiotelemeters. O2 consumption rate was measured by using gas chromatography. In a previous study (S. R. Kayar and E. C. Parker. J. Appl. Physiol. 82: 988–997, 1997), we analyzed the O2 pulse, i.e., the O2 consumption rate per heart beat, in the same animals. By multivariate regression analysis, we identified variables that were significant to O2 pulse: body surface area, chamber temperature, core temperature, and pressure. In this study, inclusion of ATw made a significantly better model with fewer variables. After normalizing for chamber temperature and pressure, the O2 pulse increased with increasing ATw in heliox ( P = 0.001) but with decreasing ATw in hydrox ( P < 0.001). Thus ATw is associated with the differences in O2 pulse for animals breathing heliox vs. hydrox. |
| Databáze: | OpenAIRE |
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