Salivary testosterone and immunoglobulin A were increased by resistance training in adults with Down syndrome
| Autor: | J.R. Alvero-Cruz, Natalia García, Ignacio Rosety, Rocío Toro, M. Rosety, T. Rodriguez-Pareja, Francisco Javier Ordonez, Gabriel Fornieles, S. Elosegui, M.A. Rosety, J.M. Rosety, Manuel Rosety-Rodriguez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Immunoglobulin A
Male Saliva Hydrocortisone Physiology Down syndrome Stanford-Binet Test Biochemistry Cortisol law.invention Body Mass Index Randomized controlled trial law Task Performance and Analysis Medicine Testosterone General Pharmacology Toxicology and Pharmaceutics lcsh:QH301-705.5 lcsh:R5-920 biology General Neuroscience General Medicine Circuit-Based Exercise lcsh:Medicine (General) Adult Adolescent Immunology Biophysics Ocean Engineering Enzyme-Linked Immunosorbent Assay Humans Clinical Investigation business.industry Testosterone (patch) Cell Biology medicine.disease Resistance training lcsh:Biology (General) Immunoglobulin A Secretory biology.protein Sedentary Behavior business Body mass index Hormone |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 47, Iss 4, Pp 345-348 (2014) Brazilian Journal of Medical and Biological Research |
| Popis: | This study was designed to assess the influence of resistance training on salivary immunoglobulin A (IgA) levels and hormone profile in sedentary adults with Down syndrome (DS). A total of 40 male adults with DS were recruited for the trial through different community support groups for people with intellectual disabilities. All participants had medical approval for participation in physical activity. Twenty-four adults were randomly assigned to perform resistance training in a circuit with six stations, 3 days per week for 12 weeks. Training intensity was based on functioning in the eight-repetition maximum (8RM) test for each exercise. The control group included 16 age-, gender-, and BMI-matched adults with DS. Salivary IgA, testosterone, and cortisol levels were measured by ELISA. Work task performance was assessed using the repetitive weighted-box-stacking test. Resistance training significantly increased salivary IgA concentration (P=0.0120; d=0.94) and testosterone levels (P=0.0088; d=1.57) in the exercising group. Furthermore, it also improved work task performance. No changes were seen in the controls who had not exercised. In conclusion, a short-term resistance training protocol improved mucosal immunity response as well as salivary testosterone levels in sedentary adults with DS. |
| Databáze: | OpenAIRE |
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