Mucoadhesive cationic lipid-based Flavobacterium oreochromis nanoencapsulation enhanced the efficacy of mucoadhesive immersion vaccination against columnaris disease and strengthened immunity in Asian sea bass (Lates calcarifer)

Autor: Anurak Bunnoy, Patcharapong Thangsunan, Putita Chokmangmeepisarn, Teerapong Yata, Nawanith Klongklaew, Nopadon Pirarat, Sirikorn Kitiyodom, Prapansak Srisapoome, Channarong Rodkhum
Rok vydání: 2022
Předmět:
Zdroj: Fish & Shellfish Immunology. 127:633-646
ISSN: 1050-4648
DOI: 10.1016/j.fsi.2022.06.059
Popis: Columnaris is a bacterial disease, found in freshwater fish, caused by Flavobacterium oreochromis. The disease has a devastating impact on a range of cultured and wild freshwater fish species e.g. Lates calcarifer (Asian sea bass), which is a serious economic losses to the freshwater aquaculture in Thailand. The disease can be prevented by an efficacious vaccine, however, no licensed effective vaccine is available to date. Current study was based on the development of a novel mucoadhesive nano-encapsulated vaccine (EncapFlavoNP
Databáze: OpenAIRE