Occupational exposure to chemicals and risk of thyroid cancer in Sweden
| Autor: | Nuria Aragonés, Virginia Lope, Gonzalo López-Abente, Agustín Silva-Mato, Marina Pollán, Nils Plato, Per Gustavsson, Beatriz Pérez-Gómez |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Risk medicine.disease_cause Occupational safety and health Cohort Studies Toxicology Swedish population Risk Factors Occupational Exposure Environmental health medicine Humans Poisson Distribution Thyroid Neoplasms Occupations Thyroid cancer Thyroid neoplasm Retrospective Studies Sweden business.industry Public Health Environmental and Occupational Health Cancer medicine.disease Carcinogens Environmental Shoes Occupational Diseases Increased risk Relative risk Solvents Female Occupational exposure business |
| Zdroj: | International Archives of Occupational and Environmental Health. 82:267-274 |
| ISSN: | 1432-1246 0340-0131 |
| DOI: | 10.1007/s00420-008-0314-4 |
| Popis: | PURPOSE: To explore thyroid cancer (TC) risk in the Swedish population, associated with occupational exposure to certain chemicals. METHODS: National cancer and death registries were used to follow-up (1971-1989) all Swedish workers employed in the 1970 census. Each combination of occupation and industry was linked to a Swedish job-exposure matrix (JEM), with exposure to 13 chemicals classified as "possible exposure", "probable exposure" or "unexposed". Relative risks were obtained using Poisson models adjusted for age, period and geographical area. A second analysis was performed, in which adjustment was additionally made for simultaneous exposure to other matrix chemicals and ionising radiations. RESULTS: Probable exposure to solvents among women displayed an increased risk (RR = 1.91; 95%CI:1.05-3.45), mainly due to a higher risk observed among shoe-cutters, lasters and sewers engaged in shoe-making. CONCLUSIONS: Exposure to solvents, used mainly in the shoe and leather industry, seems to be associated with excess TC among women. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink