Plasma progesterone kinetics following surgical treatment of ectopic pregnancies
| Autor: | Gérôme Descargues, Antoine Gravier, Fabrice Voisin, Aymeric Mantel, Annick Legrand, Jean Paul Lemoine, Loïc Marpeau |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Salpingostomy medicine.drug_class medicine.medical_treatment Sensitivity and Specificity Pregnancy Internal medicine Salpingectomy Blood plasma medicine Humans Chorionic Gonadotropin beta Subunit Human Prospective Studies Treatment Failure Prospective cohort study Fallopian Tubes Progesterone Ectopic pregnancy biology business.industry Obstetrics and Gynecology medicine.disease Kinetics Endocrinology Reproductive Medicine biology.protein Female Pregnancy Tubal Gonadotropin business ATP synthase alpha/beta subunits |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 97:65-70 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/s0301-2115(00)00505-4 |
| Popis: | Objectives : Comparative study of plasma progesterone and βHCG kinetics following surgical treatment of ectopic pregnancy. Study Design : Prospective study involving 62 patients with tubal ectopic pregnancies. Study of the kinetics of plasma progesterone and βHCG, and the correlation coefficient between plasma progesterone and βHCG levels during post-operative follow-up. Results : Thirty-nine patients were treated by salpingostomy and 23 by salpingectomy. Analyzing the βHCG kinetics according to treatment revealed that both curves were convergent on day 2. Progesterone kinetics differed greatly in that they appeared “parallel and confused”. Analyzing the correlation between βHCG and progesterone levels proved the absence of a significant link. Conclusions : Studying the kinetics of plasma progesterone after surgical treatment of ectopic pregnancies revealed a fast decrease in progesterone. Statistical analysis of the progesterone concentration showed that post-operative kinetics is fully independent from that of βHCG. Progesterone therefore cannot be substituted to βHCG for post-operative follow-up. |
| Databáze: | OpenAIRE |
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