Mediterranean diet improves embryo yield in IVF: a prospective cohort study

Autor: Yi-Hua Lin, Lan Fu, Wei-Ping Qian, Xiangli Zou, Dongxia Lin, Hong-mei Sun, Change Zou, Fanhua Meng
Rok vydání: 2019
Předmět:
Adult
Male
0301 basic medicine
Infertility
medicine.medical_specialty
Pregnancy Rate
lcsh:QH471-489
Mediterranean diet
medicine.medical_treatment
Embryo yield
Reproductive medicine
Fertilization in Vitro
Diet
Mediterranean
lcsh:Gynecology and obstetrics
03 medical and health sciences
0302 clinical medicine
Endocrinology
Pregnancy
Surveys and Questionnaires
In vitro fertilization
Bayesian multivariate linear regression
Internal medicine
medicine
Humans
lcsh:Reproduction
Prospective Studies
Prospective cohort study
lcsh:RG1-991
030219 obstetrics & reproductive medicine
In vitro fertilisation
business.industry
Research
Obstetrics and Gynecology
Embryo
Embryo
Mammalian
medicine.disease
Treatment Adherence and Compliance
030104 developmental biology
Reproductive Medicine
Multivariate Analysis
Linear Models
Female
Observational study
business
Infertility
Female
Developmental Biology
Zdroj: Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-7 (2019)
Reproductive Biology and Endocrinology : RB&E
ISSN: 1477-7827
DOI: 10.1186/s12958-019-0520-9
Popis: Background Mediterranean diet (MediDiet) had been reported to be beneficial to human health. However the relationship between diet pattern and outcomes of in vitro fertilization (IVF) treatment was scarcely researched. This study was aimed to explore the correlation between MediDiet pattern of infertile women and their clinical outcomes of IVF cycles. Methods An observational prospective cohort study was conducted in the reproductive center from September 2016 to December 2017. Seven hundred infertile women about to undergo IVF treatment were asked to conduct a questionnaire survey. Patients were assigned to higher MediDiet adherence group or lower MediDiet adherence group according to their Mediterranean diet scores. Laboratory parameters and clinical outcomes were compared and those were different between groups were further analyzed for their relationship with MediDiet adherence. Results A total of 590 women were finally included in the study. According to MediDiet scores, 228 participants were categorized as higher MediDiet adherence group and 362 others as lower MediDiet adherence group. No significant differences were found in baseline characteristics between groups. Higher MediDiet adherence group showed larger number of embryos available (8.40 ± 5.26 vs 7.40 ± 4.71, P = 0.028). Clinical pregnancy rate and implantation rate were similar between the two groups. In further correlation tests and multivariate linear regression analysis, number of fertilized oocytes and embryo yield were positively correlated to MediDiet adherence of participants. Conclusion Infertile women with greater adherence to Mediterranean diet pattern were likely to obtain more embryos available in IVF cycle.
Databáze: OpenAIRE
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