Changes in renal function following Roux-en-Y gastric bypass: a prospective study
| Autor: | Isam N. Hamdallah, Jennifer N. Wu, Jacqueline Craig, Mohamed R. Ali, Hazem Shamseddeen, Jorge L. Zelada Getty, Roger K. Low |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Gastric bypass Urology Gastric Bypass Renal function Urine Body Mass Index chemistry.chemical_compound Internal medicine Diabetes mellitus Weight Loss medicine Humans Prospective Studies Prospective cohort study Metabolic Syndrome Creatinine Nutrition and Dietetics business.industry Middle Aged medicine.disease Roux-en-Y anastomosis Obesity Morbid Endocrinology Treatment Outcome chemistry Hypertension Population study Surgery Female Kidney Diseases business Glomerular Filtration Rate |
| Zdroj: | Obesity surgery. 22(7) |
| ISSN: | 1708-0428 |
| Popis: | Studies of the impact of Roux-en-Y gastric bypass (RYGB) on renal function have shown mixed results. We constructed this prospective repeated-measures controlled study to characterize this response and identify the best method of gauging renal function in this setting. Clinical data, serum creatinine (SC), and 24-h urine were collected 1 week before and 6 months following RYGB. Glomerular filtration rate (GFR) was calculated utilizing the Modification of Diet in Renal Disease formula. Creatinine clearance (CCL) was measured as a 24-h collection (24CCL) and calculated by the Cockcroft-Gault (CG) formula. The study population of 37 patients (81% women) had a mean age of 47 ± 11 years, had mean BMI of 47.6 ± 6.3 kg/m2, and achieved a mean % excess weight loss (EWL) of 60.9 ± 17.1%. SC decreased from 0.83 ± 0.21 mg/dl to 0.72 ± 0.16 mg/dl (p |
| Databáze: | OpenAIRE |
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