Dopamine-selective potentiometric responses by new ditopic sensory elements based on a hexahomotrioxacalix[3]arene
| Autor: | Kazunori Odashima, Naohiro Shirai, Shin-ichi Ikeda, Ryosuke Saijo, Saori Tsunekawa, Hiroyuki Murakami |
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| Rok vydání: | 2007 |
| Předmět: |
inorganic chemicals
Magnetic Resonance Spectroscopy Dopamine Clinical Biochemistry Potentiometric titration Substituent Pharmaceutical Science Biosensing Techniques Biochemistry Medicinal chemistry Membrane Potentials chemistry.chemical_compound Molecular recognition Drug Discovery Calixarene Organic chemistry Polyvinyl Chloride Molecular Biology Organic Chemistry Membranes Artificial Kinetics Membrane chemistry Potentiometry Molecular Medicine Indicators and Reagents Calixarenes Selectivity Boronic acid Cyclophane |
| Zdroj: | Bioorganic & Medicinal Chemistry Letters. 17:767-771 |
| ISSN: | 0960-894X |
| DOI: | 10.1016/j.bmcl.2006.10.073 |
| Popis: | New ditopic sensory elements 2 and 3 for catecholamines based on a hexahomotrioxacalix[3]arene, with a boronic acid substituent appended, were designed and synthesized. As an interesting mode of molecular recognition at membrane surfaces, the host, when incorporated into poly(vinyl chloride) (PVC) liquid membranes, displayed excellent potentiometric selectivity for dopamine over other catecholamines (noradrenaline and adrenaline) and inorganic cations (Na+, K+, and NH4+). |
| Databáze: | OpenAIRE |
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