A New fatty acid and some triterpenoids from propolis of Nkambe (North-West Region, Cameroon) and evaluation of the antiradical scavenging activity of their extracts
| Autor: | Joseph Tanyi Mbafor, Jean Noël Nyemb, Abakar Ali Mahamat, Henoumont Celine, Emmanuel Talla, Isaac Silvère Gade, Laurent Sophie, Alfred Tamfu Ngenge |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
0303 health sciences Traditional medicine hexatriacontanoic acid 010405 organic chemistry Chemistry Fatty acid polyphenol content antiradical activity on dpph General Chemistry Propolis 01 natural sciences 0104 chemical sciences propolis lcsh:Chemistry 03 medical and health sciences Triterpenoid lcsh:QD1-999 North west Materials Chemistry Scavenging 030304 developmental biology |
| Zdroj: | Open Chemistry, Vol 18, Iss 1, Pp 239-243 (2020) |
| ISSN: | 2391-5420 |
| DOI: | 10.1515/chem-2020-0016 |
| Popis: | The aim of this work was to evaluatein vitroantiradical scavenging activity of propolis from Nkambe (North-West, Cameroon). The polyphenol content of the acetone extract was evaluated using the Folin-Ciocalteu reagent as 0.166±0.008 gGAE/100 gRM. Antiradical scavenging activity of hexane and acetone extracts was carried out on DPPH using ascorbic acid as standard. The results showed that the extracts possess antiradical activity with IC50of 141 μg/mL and 267 μg/mL for acetone and hexane extracts, respectively. The column chromatography separation on silica gel of the hexane fractionyielded compounds1to3. The structures of these compounds were elucidated by NMR and mass spectrometry data as Lupenone (1), a mixture ofαandß-Amyrin (2) and lastly Hexatriacontanoic acid (3) which was described for the first time from propolis. |
| Databáze: | OpenAIRE |
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