Detection of resistance genes and susceptibility patterns in Bacteroides and Parabacteroides strains
Autor: | Regina Maria Cavalcanti Pilotto Domingues, Priscilla L.S. Guimarães, Joaquim dos Santos-Filho, Geraldo Renato de Paula, Renata F. Boente, Eliane de Oliveira Ferreira, Jean-Philippe Emond, Karla Rodrigues Miranda, Laís S. Falcão, Livia Q. Ferreira, Jessica Manya B. D. Vieira, David E. Barroso |
---|---|
Rok vydání: | 2009 |
Předmět: |
Imipenem
Tetracycline Microbial Sensitivity Tests medicine.disease_cause Microbiology Antibiotic resistance Ampicillin Metronidazole Drug Resistance Bacterial medicine Bacteroides Humans Cefoxitin biology Parabacteroides biology.organism_classification Bacteroides Infections Anti-Bacterial Agents Intestines Infectious Diseases Genes Bacterial Parabacteroides distasonis Brazil medicine.drug |
Zdroj: | Anaerobe. 16(3) |
ISSN: | 1095-8274 |
Popis: | Susceptibility to five antimicrobials was determined for Bacteroides spp. (n = 52) and Parabacteroides distasonis (n = 8). All isolates were susceptible to metronidazole. The resistance rates to ampicillin, cefoxitin, tetracycline and clindamycin were 98%, 9.6%, 65.3% and 19.2% of the Bacteroides strains, respectively. The genes cepA, cfiA, cfxA, tetQ, ermF and nim were found in 69.2%, 17.3% 9.6%, 50%, 7.7% and 3.8% for these strains respectively. All P. distasonis strains were resistant to ampicilin. Cefoxitin, tetracycline and clindamycin resistance rates were 75%, 87.5% and 50%, respectively. The ermF and nim genes were absent and 37.5%, 12.5%, 12.5% and 87.5% of this strains possessed cepA, cfiA, cfxA and tetQ genes, respectively. Ten cfiA gene positive strains of Bacteroides and Parabacteroides were submitted to E-test with imipenem and amoxicillin-clavulanate. The resistance rate to imipenem was 4.1% and 8.3% to amoxicillin-clavulanate. This feature is for the first time described in Brazil. |
Databáze: | OpenAIRE |
Externí odkaz: |