Cost-effectiveness of nutritional intervention on healing of pressure ulcers
| Autor: | Takehiko Ohura, Akinori Hisashige |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Cost effectiveness Cost-Benefit Analysis MEDLINE Critical Care and Intensive Care Medicine law.invention Japan Quality of life Randomized controlled trial law Intervention (counseling) Humans Medicine Aged Randomized Controlled Trials as Topic Aged 80 and over Pressure Ulcer Wound Healing Nutrition and Dietetics Cost–benefit analysis business.industry Quality-adjusted life year Treatment Outcome Economic evaluation Quality of Life Physical therapy Female Quality-Adjusted Life Years business Diet Therapy Follow-Up Studies |
| Zdroj: | Clinical Nutrition. 31:868-874 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/j.clnu.2012.04.013 |
| Popis: | Summary Background & aims Pressure ulcers not only affect quality of life among the elderly, but also bring a large economic burden. There is limited evidence available for the effectiveness of nutritional interventions for treatment of pressure ulcers. In Japan, recently, a 60-patient randomized controlled trial of nutritional intervention on pressure ulcers demonstrated improvement in healing of pressure ulcers, compared with conventional management. To evaluate value for money of nutritional intervention on healing of pressure ulcers, cost-effective analysis was carried out using these trial results. Methods The analysis was carried out from a societal perspective. As effectiveness measures, pressure ulcer days (PUDs) and quality-adjusted life years (QALYs) were estimated. Prevalence of pressure ulcers was estimated by the Kaplan–Meier method. Utility score for pressure ulcers is derived from a cross-sectional survey among health professionals related to pressure ulcers. Costs (e.g., nutritional interventions and management of pressure ulcers) were estimated from trial data during observation and follow-up. Stochastic and qualitative sensitivity analyses were performed to examine the robustness of results. Results For observation (12 weeks) and follow-up (12-week observation plus 4-week follow-up), nutritional intervention reduced PUDs by 9.6 and 16.2 per person, and gained 0.226 × 10−2 QALYs and 0.382 × 10−2 QALYs per person, respectively. In addition, costs were reduced by $542 and $881 per person, respectively. This means nutritional intervention is dominant (cost savings and greater effectiveness). The sensitivity analyses showed the robustness of these results. Conclusion Economic evaluation of nutritional intervention on healing pressure ulcers from a small randomized controlled trial showed that this intervention is cost saving with health improvement. Further studies are required to determine whether this is a cost-effective intervention for widespread use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect