Ramsay Hunt syndrome: a rare complication of herpes zoster infection in a lung cancer patient
| Autor: | Toine Mercier, Griet Deslypere, Kristiaan Nackaerts |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Lung Neoplasms Hearing loss viruses Herpes Zoster Oticus Adenocarcinoma of Lung medicine.disease_cause Vestibulocochlear nerve 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine pemetrexed vestibulocochlear nerve Aged integumentary system Ramsay Hunt syndrome business.industry Liver Neoplasms Varicella zoster virus virus diseases General Medicine Dermatology Rash Facial nerve Herpes zoster oticus 030220 oncology & carcinogenesis facial nerve Virus Activation medicine.symptom Complication business |
| Zdroj: | Acta Clinica Belgica. 74:355-358 |
| ISSN: | 2295-3337 1784-3286 |
| DOI: | 10.1080/17843286.2018.1517076 |
| Popis: | Objectives: Ramsay Hunt syndrome (RHS) is a rare complication of varicella zoster virus (VZV) reactivation with high morbidity, requiring swift and specific treatment. Methods: We discuss the epidemiology, diagnosis and treatment of RHS using a case report of a cancer patient who presented with disseminated VZV reactivation, including RHS. Results: A 68-year old man with stage IV lung adenocarcinoma, for which he received pemetrexed maintenance chemotherapy, presented to the emergency department with a progressive skin rash despite broad spectrum antibiotics, vertigo, and diminished hearing. Valacyclovir was started for a varicella zoster virus (VZV) reactivation. Despite antiviral therapy, his symptoms progressed with late appearance of vesicles in the external ear canal, leading to a diagnosis of Ramsay Hunt syndrome (RHS). Conclusion: RHS is a rare complication of VZV reactivation and can lead to peripheral facial nerve palsy, hearing loss, vestibular problems, and vesicles in the dermatome of the cranial nerve. Timely initiation of steroids and antiviral therapy lead to recovery of the facial nerve in >75% of cases, although the optimal therapy is still unclear. ispartof: ACTA CLINICA BELGICA vol:74 issue:5 pages:355-358 ispartof: location:England status: published |
| Databáze: | OpenAIRE |
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