Good outcome in HIV-infected refugees after resettlement in New Zealand: population study
| Autor: | AM Reeve, R. J. H. Ingram, Ellis-Pegler Rb, Sarah Nisbet, Susan McAllister, Sally A. Roberts, Andrew Woodhouse, Mark G. Thomas |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Tuberculosis Adolescent Anti-HIV Agents Refugee HIV Infections AIDS Epidemiology Comorbidity Median follow-up Internal Medicine Medicine Humans Infectious disease (athletes) Child Retrospective Studies Medical Audit Refugees business.industry Transmission (medicine) Emigration and Immigration Middle Aged medicine.disease Treatment Outcome Child Preschool Immunology Population study Female business Viral load New Zealand |
| Zdroj: | Internal medicine journal. 37(5) |
| ISSN: | 1445-5994 |
| Popis: | Background: The aims of this study were to determine the clinical characteristics on arrival and the subsequent clinical outcome of HIV-infected UN quota refugees who settled in New Zealand during the last 11 years and to estimate their rate of HIV transmission. Methods: A population study was conducted. Data were provided by the Mangere Refugee Resettlement Centre, the infectious disease physicians caring for the subjects, the New Zealand AIDS Epidemiology Group and laboratories carrying out HIV viral load assays. Results: One hundred of 7732 (1.3%) UN quota refugees were HIV positive; mean age 30 years, 56% were men, median initial CD4 count was 320 (range 20–1358). HIV infection was most commonly acquired by heterosexual intercourse (74%). The median follow up was 5.0 years (range 1 month to 9.7 years). Five died and 15 subjects had 16 AIDS-defining illnesses, most commonly tuberculosis (n = 10). Sixty subjects commenced highly active antiretroviral therapy of whom 36/59 (61%) had an undetectable HIV viral load after 1 year of treatment. None of the six children born to HIV-infected women in New Zealand were infected. There were two known cases of horizontal transmission of HIV infection. Conclusion: Although HIV-infected quota refugees often have to overcome severe social, cultural and financial handicaps, their clinical outcome is generally very good, with response rates to highly active antiretroviral therapy that are similar to other patient groups. Furthermore, they have not been a significant source of transmission of HIV infection after resettlement in New Zealand. |
| Databáze: | OpenAIRE |
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