Elevation of Serum CEA in Patients with Squamous Cell Carcinoma of the Anus
| Autor: | Steven A. Lee-Kong, Ravi P. Kiran, Daniel L. Feingold, Alfred I. Neugut, Daniel S. O’Neil, Gabriel T. Raab, David P. Horowitz |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male Cancer Research medicine.medical_specialty endocrine system diseases Gastroenterology 03 medical and health sciences 0302 clinical medicine Carcinoembryonic antigen Internal medicine medicine Anal cancer Humans Basal cell In patient neoplasms Neoplasm Staging biology business.industry Cancer General Medicine medicine.disease Anus Anus Neoplasms Prognosis digestive system diseases Carcinoembryonic Antigen Up-Regulation 030104 developmental biology medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis biology.protein Carcinoma Squamous Cell Cancer biomarkers Female Neoplasm Grading business CEA measurement |
| Zdroj: | Cancer investigation. 37(7) |
| ISSN: | 1532-4192 |
| Popis: | The proportion of anal cancer cases that produce elevated carcinoembryonic antigen (CEA) levels is not well described in the medical literature. In this study, we used electronic health record data from a single urban cancer center to identify patients from 2004-2018 with anal cancer who have also had a pre-initial treatment CEA measurement. We identified 40 patients who met our eligibility criteria. Of those, 11 (27.5%) had an elevated pretreatment CEA. Elevated CEA was not associated with any of the clinical or demographic covariates; however, three out of five patients with a recurrence had an elevated CEA. |
| Databáze: | OpenAIRE |
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