The Relationship Between Cognitive Dysfunction Through THINC-Integrated Tool (THINC-it) and Psychosocial Function in Chinese Patients With Major Depressive Disorder
| Autor: | Han Han, Yanyan Hou, Shuqiao Yao, Shaohua Hu, Qi Zhou, Xin Yu, Roger S. McIntyre, Chuan Shi |
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| Rok vydání: | 2021 |
| Předmět: |
Psychiatry
MDD Work productivity business.industry RC435-571 THINC-it Paper version Cognition work productivity medicine.disease Correlation Psychiatry and Mental health Chinese version psychosocial function medicine Major depressive disorder In patient Psychosocial function business cognitive function Original Research Clinical psychology |
| Zdroj: | Frontiers in Psychiatry Frontiers in Psychiatry, Vol 12 (2021) |
| ISSN: | 1664-0640 |
| DOI: | 10.3389/fpsyt.2021.763603 |
| Popis: | Background: Herein, we validate the psychometric properties of the Chinese version of the THINC-integrated tool (THINC-it) as a screening tool for cognitive deficits in patients with major depressive disorder. The primary aim of this study is to determine whether cognitive deficits as detected by the THINC-it tool in adults with major depressive disorder (MDD) are associated with workplace productivity and/or psychosocial function.Methods: Subjects aged 18–65 (n = 91) with MDD were evaluated and compared to age-, sex- and education- matched healthy controls (n = 95). Symptoms of cognitive dysfunction, workplace productivity, and psychosocial function were measured using the THINC-it tool, Hamilton Depression Scale (HAMD), Sheehan Disability Scale (SDS), The Work Productivity and Activity Impairment questionnaire- Specific Health Problem (WPAI-SHP).Results: There were significant differences in THINC-it scores (p < 0.01), the average of HAMD total score (p < 0.01) and all aspects of SDS (p < 0.01) between two groups. There were significant differences in the four aspects of WPAI between the two groups in the employed status (p r ranging from 0.255 to 0.386, p r ranging |
| Databáze: | OpenAIRE |
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