Progression of visual field in patients with primary open-angle glaucoma - ProgF study 1

Autor:	Hussam El Chehab, Florent Aptel, Jean-Paul Romanet, M. Delbarre, Jean-Paul Renard, Nishal Aryal-Charles, Jean-Marie Giraud, Christophe Chiquet
Rok vydání:	2015
Předmět:	Male medicine.medical_specialty genetic structures Open angle glaucoma Population Vision Disorders Ocular hypertension Glaucoma Risk Factors Ophthalmology medicine Humans education Antihypertensive Agents Intraocular Pressure Aged Aged 80 and over education.field_of_study business.industry General Medicine Middle Aged medicine.disease eye diseases Visual field Disease Progression Visual Field Tests Female Ocular Hypertension sense organs Visual Fields business Event analysis Glaucoma Open-Angle Progressive disease Cohort study
Zdroj:	Acta Ophthalmologica. 93:e615-e620
ISSN:	1755-375X
DOI:	10.1111/aos.12788
Popis:	Purpose To evaluate the visual field rate of progression of patients with treated ocular hypertension (OHT) and primary open-angle glaucoma (POAG) in clinical practice, using the mean deviation (MD) and the visual field index (VFI). Methods Non-interventional cohort study. From a large multicentre database representative of the French population, 441 eyes of 228 patients with treated OHT or POAG followed up at least 6 years with Humphrey 24.2 Sita-Standard visual field examination at least twice a year were identified. From initial data, eyes were classified in five groups: 121 with OHT, 188 with early glaucoma (MD greater than −6 dB), 45 with moderate glaucoma (MD −6 to −12 dB), 41 with advanced glaucoma (MD −12 to −18 dB) and 46 with severe glaucoma (MD less than −18 dB). Rate of progression during the follow-up period was calculated using the trend analysis of the Guided Progression Analysis software. Results The mean duration of follow-up was 8.4 ± 2.7 years and the mean number of visual field, 18.4 ± 3.5. In eyes with OHT, rate of progression was −0.09 dB/year (−0.17%VFI/year). In eyes with POAG, rate of progression was −0.32 dB/year (−0.83%VFI/year) in eyes with early glaucoma, −0.52 dB/year (−1.81%VFI/year) in moderate glaucoma, −0.54 dB/year (−2.35%VFI/year) in advanced glaucoma and −0.45 dB/year (−1.97%VFI/year) in severe glaucoma. In eyes with POAG, a significant progression (p
Databáze:	OpenAIRE
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