Highly sustainable catalytic dehydrogenation of alcohols with evolution of hydrogen gas

Autor:	M. P. J. Donners, L.A. Hulshof, G.B.W.L. Ligthart, J Jan Meuldijk, Jef A. J. M. Vekemans, R. H. Meijer
Přispěvatelé:	Macromolecular and Organic Chemistry, Chemical Engineering and Chemistry, Macro-Organic Chemistry
Rok vydání:	2003
Předmět:	Hydrogen Organic Chemistry High selectivity Decarbonylation chemistry.chemical_element General Medicine Photochemistry Biochemistry Catalysis chemistry Transition metal Drug Discovery Organic chemistry Dehydrogenation Aldol condensation
Zdroj:	Tetrahedron Letters, 44(7), 1507-1509. Elsevier
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(02)02842-3
Popis:	The catalytic dehydrogenation of alcohols into aldehydes and ketones in the absence of H-acceptors was studied with several transition metal catalysts in order to develop a large-scale procedure. Applying Ru(OCOCF3)2(CO)(PPh3)2, the so called Robinson catalyst, several secondary alcohols could be dehydrogenated with high selectivity into the corresponding ketones in relatively short reaction times. Highly effective atom utilization could be realized avoiding solvents and giving hydrogen gas as the sole by-product. However, in contrast to Robinson's work the catalytic dehydrogenation of primary alcohols appeared to be problematic due to decarbonylation with concomitant catalyst deactivation and aldol condensation under the strong acid or basic conditions applied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bd14681dd46855eb8b07a7bedb0dd3 https://doi.org/10.1016/s0040-4039(02)02842-3 Zobrazit plný text záznamu Full Text from ScienceDirect