Diffusion-weighted imaging (DWI) of the liver in assessing chronic liver disease: effects of the presence and the degree of ascites on ADC values
| Autor: | Cemile Ayşe Görmeli, Metin Dogan, Zeynep Özdemir, Aysegul Kahraman, Bayram Kahraman, Fatih Ozdemir |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Urology Spleen Chronic liver disease Gastroenterology 030218 nuclear medicine & medical imaging 03 medical and health sciences Liver disease 0302 clinical medicine Internal medicine Ascites Humans Medicine Effective diffusion coefficient Radiology Nuclear Medicine and imaging Aged Retrospective Studies Aged 80 and over Radiological and Ultrasound Technology medicine.diagnostic_test Echo-Planar Imaging business.industry Liver Diseases Case-control study Magnetic resonance imaging Middle Aged Hepatology medicine.disease body regions Diffusion Magnetic Resonance Imaging medicine.anatomical_structure Case-Control Studies 030220 oncology & carcinogenesis Chronic Disease Female Radiology medicine.symptom business |
| Zdroj: | Abdominal Radiology. 41:56-62 |
| ISSN: | 2366-0058 2366-004X |
| Popis: | The aim of this study was to determine the correlation between the liver and spleen apparent diffusion coefficient (ADC) values of patients with chronic liver disease and the presence and the degree of ascites. In this retrospective study, we assessed 107 patients with chronic liver disease and 39 control subjects who underwent upper abdominal MR imaging including echo-planar diffusion-weighted imaging (DWI). Among the 107 cirrhotic patients, 56 were classified as group 1, 25 as group 2, and 26 as group 3 according to the absence, the presence of minimal, and the presence of massive ascites, respectively. The scores of model for end-stage liver disease (MELD) were matched between groups as the standard reference. The liver ADC, spleen ADC, and normalized liver ADC values were compared between the control group and patients’ groups. Patients with massive ascites had significantly higher MELD score compared with the other groups. The MELD score was also significantly higher in patient groups than in control group. The liver and normalized liver ADCs of patients’ groups were significantly lower than that of the control group. With some overlap among groups, the measured ADC values decreased as the amount of the ascites increased, and these relationships were statistically significant. Furthermore, compared to control group, patients with massive ascites had significantly higher spleen ADCs. Our results indicate that the ADC value of the liver and spleen correlates with the presence and the degree of ascites in patients with chronic liver disease, and merits further study. |
| Databáze: | OpenAIRE |
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