Weekly and yearly rhythms in plasma fibrinogen in hospitalized male military veterans
| Autor: | Eugene L. Kanabrocki, Jeff T. Bean, Thelma J. Crosby, Carol Riley, John G. Demakis, Parvez Shirazi, John H. Olwin, W. Fraser Bremner, Nancy J. Fabbrini, Joseph G. Ringelstein, Hunter Mermall, Jane L.H.C. Third, Robert B. Sothern |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Periodicity medicine.medical_specialty Time Factors Fibrinogen Tissue plasminogen activator Sudden death Internal medicine Blood plasma medicine Humans Myocardial infarction Circadian rhythm Aged Analysis of Variance business.industry Incidence (epidemiology) Middle Aged medicine.disease Hospitalization Military Personnel Cardiology Illinois Seasons Cardiology and Cardiovascular Medicine business Circaseptan medicine.drug |
| Zdroj: | The American Journal of Cardiology. 76:628-631 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(99)80173-8 |
| Popis: | The variation in plasma fibrinogen level demonstrating prominent circaseptan and circannual cycles is clinically relevant. There is a correlation between increasing level of fibrinogen and other hemostatic factors and risk of myocardial infarction and sudden death. The circaseptan and circannual cycles in fibrinogen concentration described in this study may help to explain further the variation in frequency of coronary events. Furthermore, the recent demonstration of a circadian pattern in the efficacy of tissue plasminogen activator, with peak efficacy occurring at 2000 hours--10 hours after the peak incidence of myocardial infarction--implies that further patterns to coronary artery syndromes may be predicted and the treatment efficacy may rely on demonstrated circaseptan and circannual cycles of these events. |
| Databáze: | OpenAIRE |
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