Morbidly obese individuals with impaired fasting glucose have a specific pattern of insulin secretion and sensitivity: effect of weight loss after bariatric surgery
| Autor: | Federico Soriguer, Eduardo García-Fuentes, Jose Manuel García-Almeida, M Sol Ruiz de Adana, Isabel Cardona, Montserrat Gonzalo, Belén González-Jiménez, Juan Garcia-Arnes, Sara García-Serrano, Jose L. Gallego-Perales, Jose Rivas-Marín, M. José Garriga |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment Bariatric Surgery Morbidly obese Insulin resistance Weight loss Internal medicine Glucose Intolerance Insulin Secretion Weight Loss medicine Humans Insulin Insulin secretion Nutrition and Dietetics business.industry Fasting Glucose Tolerance Test Middle Aged medicine.disease Impaired fasting glucose Obesity Surgery Obesity Morbid Endocrinology Case-Control Studies Female Intravenous Glucose Tolerance Test medicine.symptom business Follow-Up Studies |
| Zdroj: | Obesity surgery. 16(9) |
| ISSN: | 0960-8923 |
| Popis: | Background: Obesity is often associated with hyper-secrection of insulin. Impaired fasting glucose (IFG) has recently been redefined as a fasting plasma glucose of 5.6-6.9 mmol/L. The aim of this study was to determine whether changes in insulin secretion in morbidly obese persons also commence with normal serum glucose levels. Methods: 32 morbidly obese subjects were studied before and after bariatric surgery. Measurements were made of glucose tolerance (KG), insulin sensitivity (SI), first-phase insulin release and the disposition index (DI) from a frequently sampled intravenous glucose tolerance test. Result: In morbidly obese subjects, the SI (P |
| Databáze: | OpenAIRE |
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