Serum aluminium and cobalt levels after ceramic-on-ceramic and metal-on-metal total hip replacement
| Autor: | M. Gruber, Vanee Meisinger, Alexander Grübl, Rainer Kotz, M. Weissinger, Wolfram Brodner, Florian Gottsauner-Wolf, Alexander Giurea, G. Pöll, A. Gleiss |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male inorganic chemicals Ceramics medicine.medical_specialty Arthroplasty Replacement Hip medicine.medical_treatment Total hip replacement chemistry.chemical_element Avascular necrosis Prosthesis Design Metal Femur Head Necrosis Aluminium Aluminium level Osteoarthritis medicine Humans Orthopedics and Sports Medicine Femur Prospective Studies Aged Aged 80 and over business.industry Acetabulum Mean age Cobalt Middle Aged medicine.disease Arthroplasty Surgery Treatment Outcome chemistry Metals visual_art visual_art.visual_art_medium Female business Nuclear medicine Aluminum |
| Zdroj: | The Journal of Bone and Joint Surgery. British volume. :1003-1005 |
| ISSN: | 2044-5377 0301-620X |
| DOI: | 10.1302/0301-620x.88b8.17870 |
| Popis: | In a randomised study, 28 patients with a mean age of 62.2 years (32 to 81) with osteoarthritis or avascular necrosis of the hip received either a ceramic-on-ceramic or a metal-on-metal total hip replacement. Apart from the liners the acetabular and femoral components were made of Ti-Al-Nb alloy. The serum aluminium and cobalt levels were measured before, and at one year after surgery. The 15 patients in the ceramic-on-ceramic group had a median pre-operative aluminium level of 1.3 μg/l (0.25 to 8.4) and a cobalt level below the detection limit. At one year the aluminium level was 1.1 μg/l (0.25 to 2.3) and the cobalt level was 0.4 μg/l (0.15 to 0.7). The 13 patients in the metal-on-metal group had a median pre-operative aluminium level of 1.9 μg/l (0.25 to 4.4) and a cobalt level below the detection limit. At one year the median aluminium level was 0.9 μg/l (0.25 to 3.9) whereas the cobalt level was 1.4 μg/l (0.5 to 10.5). This increase in the cobalt level at one year was significant (p < 0.001). Our findings indicate that ceramic-on-ceramic bearings do not cause elevated levels of serum aluminium in the first post-operative year. |
| Databáze: | OpenAIRE |
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