Antibiofilm activity of cashew juice pulp against Staphylococcus aureus, high performance liquid chromatography/diode array detection and gas chromatography-mass spectrometry analyses, and interference on antimicrobial drugs
| Autor: | Renan Martins dos Santos, Ezequias P. Siqueira, Marcus Vinícius Dias-Souza, Pedro H. Ferreira-Marçal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Staphylococcus aureus 030106 microbiology Titratable acid lcsh:TX341-641 medicine.disease_cause High-performance liquid chromatography Gas Chromatography-Mass Spectrometry Microbiology 03 medical and health sciences Antibiotic resistance Anti-Infective Agents pulp medicine Anacardium Food science Chromatography High Pressure Liquid Pharmacology Chemistry lcsh:RM1-950 Biofilm Antimicrobial Anti-Bacterial Agents lcsh:Therapeutics. Pharmacology Polyphenol Fruit antimicrobial Gas chromatography–mass spectrometry cashew lcsh:Nutrition. Foods and food supply Brazil Food Science |
| Zdroj: | Journal of Food and Drug Analysis, Vol 25, Iss 3, Pp 589-596 (2017) |
| ISSN: | 1021-9498 |
| Popis: | The epidemiology of Staphylococcus aureus infections has evolved in recent years, as this species is a major Gram-positive pathogen associated with healthcare services. The antimicrobial resistance of this species raises an urgent need for new treatment strategies. Fruits play important nutritional and economic roles in society, but their biological and pharmacological features are poorly explored when compared to nonedible parts of plants such as barks and leaves. In this study, we show that the cashew apple juice [cashew juice pulp (CJP)] extract is active against the planktonic cells of S. aureus strains, and for the first time, we show that CJP is also active against S. aureus biofilms. High performance liquid chromatography and gas chromatography-mass spectrometry analyses were conducted to prospect for polyphenols and free carbohydrates, respectively. Cashew apple juice, which is rich in nutrients, is widely consumed in Brazil; therefore, the quality attributes of CJPs were investigated. Samples were evaluated for pH, total titratable acidity, vitamin C levels, and total soluble solids. We also detected an antagonistic interference of CJP when it was combined with different antimicrobial drugs. |
| Databáze: | OpenAIRE |
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