Remission of long-standing livedoid vasculopathy using a whole foods plant-based diet with symptoms recurrent on re-challenge with standard Western diet
| Autor: | Bruce Duncan, Patrick C McHugh, Morgen Smith, Nicholas A. Wright |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Biopsy Case Report 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Western diet medicine Humans Re challenge Vascular Diseases 030212 general & internal medicine Symptom onset skin and connective tissue diseases Adverse effect Livedo Reticularis medicine.diagnostic_test business.industry Diet Vegetarian Plant based General Medicine Middle Aged Diet Western Community setting Female Whole food business |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2020-237895 |
| Popis: | A 63-year-old woman presented with ulcerations of both lower legs. Symptom onset was 2006. In 2013 she saw a dermatologist and a biopsy suggested livedoid vasculopathy. In 2016 a whole food plant-based diet (WFPB) was advised as a potential treatment in the community setting. The patient changed her diet accordingly, but was not otherwise treated. The symptoms remitted completely with close adherence to the WFPB diet and recurred on multiple occasions associated with poor dietary adherence. There was a self-identified dose–response relationship with degree of adherence and number and intensity of flares. There were no known adverse side effects from the diet change, although the patient felt adherence to be difficult at times. The mechanism is not completely clear; we speculate that the dietary changes directly affect vascular endothelial health, which in turn affects propensity towards a prothrombotic state. More research is needed to elucidate potential mechanisms. |
| Databáze: | OpenAIRE |
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