Calcium absorption in rheumatoid arthritis
| Autor: | Jonathan Reeve, Patricia A. Hill, J C Stevenson, J M Gumpel, G Abeyasekera, Barbara M. Ansell, P N Sambrook, S Foster |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
medicine.medical_specialty Malabsorption Calcitriol Immunology Osteoporosis chemistry.chemical_element Calcium Bone and Bones General Biochemistry Genetics and Molecular Biology Arthritis Rheumatoid Rheumatology Internal medicine medicine Humans Immunology and Allergy Recent onset Aged Calcium metabolism business.industry Middle Aged medicine.disease Menopause Endocrinology chemistry Rheumatoid arthritis Female business Tomography Emission-Computed Research Article medicine.drug |
| Zdroj: | Annals of the Rheumatic Diseases. 44:585-588 |
| ISSN: | 0003-4967 |
| DOI: | 10.1136/ard.44.9.585 |
| Popis: | Calcium absorption, assessed by a double isotope method, was found to be impaired in postmenopausal women with rheumatoid arthritis of recent onset (mean 14.2 months) compared with controls. Circulating levels of 1,25-dihydroxyvitamin D (calcitriol) were higher than in controls, suggesting a primary malabsorption of calcium in these patients. The reduction in calcium absorption correlated with several measures of disease activity, suggesting that the disease process was responsible for the intestinal defect, but an effect from non-steroidal anti-inflammatory agents cannot be excluded. A primary reduction in calcium absorption may increase the risk of osteoporosis in women with rheumatoid arthritis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|