Complications and management of elective endoscopic cyanoacrylate injection with lauromacrogol for gastric varices
| Autor: | Xiao-qing Zeng, Jie Chen, Lili Ma, Feng Li, Jian Wang, Ji Zhou, Tian-cheng Luo, Shiyao Chen, Chengfeng Liu |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Cirrhosis Polidocanol Esophageal and Gastric Varices 03 medical and health sciences 0302 clinical medicine Recurrence Ascites medicine Humans Cyanoacrylates Aged Retrospective Studies Hepatology business.industry Gastroenterology Postoperative complication Perioperative Gastric varices Middle Aged medicine.disease Portal vein thrombosis Surgery Treatment Outcome Embolism 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business Complication Gastrointestinal Hemorrhage |
| Zdroj: | European journal of gastroenterologyhepatology. 33(5) |
| ISSN: | 1473-5687 |
| Popis: | OBJECTIVE To report the complications and evaluate the risk factors of elective endoscopic cyanoacrylate injection with lauromacrogol for gastric varices in cirrhotic patients. METHODS A total of 583 elective endoscopic tissue adhesives procedures were performed in 439 patients in our hospital from January 2015 to December 2016. The clinical characteristics and complications were retrospectively collected and evaluated. RESULTS The median age was 56 ± 11 years, and 290 (66.1%) patients were male. The main etiology of liver cirrhosis was hepatitis virus (63.3%). Two hundred fifty-nine (59.0%) patients were classified as Child-Pugh Class A. Bleeding occurred in 44 patients (7.5%) during procedures. Two patients developed distant embolism (0.5%; one pulmonary, one cerebra). In perioperative period, fever was a common complication; however, only 16 cases had high fever and one case had sepsis. Bleeding was observed in 7 (1.2%) patients. Overall incidence of the major perioperative complication was 3.8%. The major postoperative complication rate was 10.4% (60/582, 26 rebleeds, 27 ascites increase, 12 new-onset portal vein thrombosis). The complication-related death was 1.6% (one death from embolism, five deaths from rebleeding, one death from refractory ascites). Injection point was the only factor related to the major perioperative complications [odds ratio (OR) = 1.581, 95% CI, 1.086-2.301; P |
| Databáze: | OpenAIRE |
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