Evaluation ofin vitro antiviral activity ofVitex Negundo L., Hyptis suaveolens (L) poit., Decalepis hamiltonii Wight & Arn., to Chikungunya virus
| Autor: | Rajarajan Swaminathan, Sangeetha Kothandan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Cytotoxicity assay Vitex negundo lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 viruses lcsh:Medicine medicine.disease_cause Decalepis hamiltonii Virus Hyptis suaveolens parasitic diseases medicine Chikungunya Cytopathic effect biology lcsh:R virus diseases biology.organism_classification Virology In vitro Infectious Diseases Antiviral assay Vero cell Chikungunya virus |
| Zdroj: | Asian Pacific Journal of Tropical Disease, Vol 4, Iss Sup 1, Pp 111-115 (2014) |
| ISSN: | 2222-1808 |
| Popis: | Objective To screen the three Indian plants for the antiviral activity to chikungunya virus since chikungunya infections are treated symptomatically without specific drugs till date. Methods In vitro cytotoxicity assay of the lyophilised extracts was assessed in vero cells for the determination of maximum non toxic concentration and in vitro antiviral assay was evaluated by the inhibition of virus induced cytopathic effect. Results Aqueous and aqueous ethanolic extracts of Hyptis suaveolens exhibited partial inhibition to Asian strain of chikungunya virus. Conclusion Of all the three plants tested for antiviral activity to both the lineages of chikungunya virus, Hyptis suaveolens were found to be effective to Asian strain of chikungunya virus. |
| Databáze: | OpenAIRE |
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