Percutaneous Treatment With Drug-Eluting Stent vs Bypass Surgery in Patients Suffering From Chronic Stable Angina With Multivessel Disease Involving Significant Proximal Stenosis in Left Anterior Descending Artery
Autor: | Zhou Yujie, Kang Junping, Jia Changqi, Dong Jianzeng, Ma Changsheng, Lv Shuzheng, Zhang Yin, Wu Jiahui, Qiao Yan, Chen Fang, Du Xin, Lv Qiang, Hu Rong, Huang Fangjiong, Gu Chengxiong, Liu Xiaohui, Nie Shaoping, Liu Xinmin, Wu Xuesi |
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Rok vydání: | 2009 |
Předmět: |
Male
Time Factors medicine.medical_treatment Myocardial Infarction Kaplan-Meier Estimate Coronary Angiography Severity of Illness Index Coronary artery disease Odds Ratio Hospital Mortality Registries Myocardial infarction Angioplasty Balloon Coronary Coronary Artery Bypass Drug-Eluting Stents General Medicine Middle Aged Treatment Outcome medicine.anatomical_structure Bypass surgery Drug-eluting stent Cardiology Female Cardiology and Cardiovascular Medicine Artery Reoperation medicine.medical_specialty Paclitaxel Revascularization Risk Assessment Angina Pectoris Internal medicine medicine Humans cardiovascular diseases Aged Proportional Hazards Models Retrospective Studies Sirolimus business.industry Coronary Stenosis Percutaneous coronary intervention Cardiovascular Agents medicine.disease Surgery Cerebrovascular Disorders Stenosis Chronic Disease business Platelet Aggregation Inhibitors |
Zdroj: | Circulation Journal. 73:1848-1855 |
ISSN: | 1347-4820 1346-9843 |
Popis: | Background: The aim of the present study was to compare the effects of drug-eluting stents (DES) and coronary artery bypass grafting (CABG) in patients suffering from chronic stable angina with multivessel disease, involving significant proximal stenosis in the left anterior descending artery (LAD). Methods and Results: All consecutive patients suffering from chronic stable angina with multivessel disease involving significant proximal LAD stenosis underwent DES implantation (n=600) or CABG (n=709) at our institution. At 2 years, the unadjusted mortality was significantly lower in the DES group than in the CABG group (2.2% vs 5.2%, P=0.004), but the adjusted risk of death was similar (odds ratio (OR) 0.74, 95%CI 0.28-1.97, P=0.555). Furthermore, both the adjusted rate of nonfatal myocardial infarction and cerebrovascular events was also comparable. However, the unadjusted and adjusted risk of major adverse cardiac cerebrovascular events in the DES was significantly higher than in the CABG (13.3% vs 9.6%, OR 2.71, 95%CI 1.56-4.74, P |
Databáze: | OpenAIRE |
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