The peptides of α -aminosuberic acid II. Synthesis of deamino-dicarba-eel-calcitonin sequence 1-9
| Autor: | Petr Maloň, Václav Čeřovský, E. Wünsch, E. Körblová, H. Stocker, Vladimír Gut, M. Žertová |
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| Rok vydání: | 2001 |
| Předmět: |
Calcitonin
chemistry.chemical_classification Eel Calcitonin Molecular Sequence Data Organic Chemistry Clinical Biochemistry Sequence (biology) Tripeptide Biochemistry Pentapeptide repeat Combinatorial chemistry Peptide Fragments Cyclic peptide Amino Acids Dicarboxylic chemistry.chemical_compound chemistry Peptide synthesis Amino Acid Sequence |
| Zdroj: | Amino Acids. 21:255-263 |
| ISSN: | 1438-2199 0939-4451 |
| DOI: | 10.1007/s007260170011 |
| Popis: | The paper describes the synthesis of Asu6-octapeptide derivatives by condensing two alternative pentapeptide fragments with Asu-containing tripeptides. After partial deprotection these linear peptides compounds are subject to cyclization experiments aimed to give the N-terminal [1-9] sequence of deamino-dicarba-eel calcitonin. This is a key substance for the semi-synthesis of the respective analogues of eel calcitonin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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