Dissociable rhythmic mechanisms enhance memory for conscious and nonconscious perceptual contents
| Autor: | Phillip (Xin) Cheng, Shrey Grover, Wen Wen, Shruthi Sankaranarayanan, Sierra Davies, Justine Fragetta, David Soto, Robert M. G. Reinhart |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Proceedings of the National Academy of Sciences of the United States of America. 119(44) |
| ISSN: | 1091-6490 2022-2025 |
| Popis: | Published October 27, 2022 Understanding the neural mechanisms of conscious and unconscious experience is amajor goal of fundamental and translational neuroscience. Here, we target the earlyvisual cortex with a protocol of noninvasive, high-resolution alternating current stimu-lation while participants performed a delayed target–probe discrimination task andreveal dissociable mechanisms of mnemonic processing for conscious and unconsciousperceptual contents. Entrainingβ-rhythms in bilateral visual areas preferentiallyenhanced short-term memory for seen information, whereasα-entrainment in the sameregion preferentially enhanced short-term memory for unseen information. The short-term memory improvements were frequency-specific and long-lasting. The results add amechanistic foundation to existing theories of consciousness, call for revisions to thesetheories, and contribute to the development of nonpharmacological therapeutics forimproving visual cortical processing. This work was supported by grants from the NIH (R01-MH114877 and R01-AG063775) and a gift from an individual philanthropist, awarded to R.M.G.R. D.S. acknowledges support from the Basque Government through the BERC 2022-2025 program and by the Spanish State Research Agency through BCBL Severo Ochoa excellence accreditation CEX2020-001010-S. |
| Databáze: | OpenAIRE |
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