Pharmacological Effects of Scutellarin, An Active Component of GenusScutellariaandErigeron: A Systematic Review
| Autor: | Jakub Strawa, Jolanta Nazaruk, Sebastian Chledzik, Katarzyna Matuszek |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Drug food.ingredient Erigeron Scutellaria media_common.quotation_subject Myocardial Ischemia Glucuronates Traditional Chinese medicine Brain Ischemia Helicobacter Infections 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Erigeron breviscapus food Alzheimer Disease Humans Medicine Apigenin media_common Scutellarin Helicobacter pylori biology Traditional medicine business.industry General Medicine biology.organism_classification Databases Bibliographic 030104 developmental biology Complementary and alternative medicine chemistry Gastritis 030220 oncology & carcinogenesis Herb Lamiaceae business Diabetic Angiopathies Phytotherapy |
| Zdroj: | The American Journal of Chinese Medicine. 46:319-337 |
| ISSN: | 1793-6853 0192-415X |
| Popis: | Flavonoid compound scutellarin (Scu) is quite frequently met in the plant kingdom, particularly in the genus Scutellaria (Lamiaceae) and Erigeron (Asteraceae). The extract of the herb of Erigeron breviscapus, containing this component in high amount, has been used for many years in traditional Chinese medicine. In recent years, studies have made great progress on the usefulness of Scu for treating various diseases by testing its mechanism of action. They support the traditional use of Scu rich plant in heart and cerebral ischemia. Scu can potentially be applied in Alzheimer’s disease, Helicobacter pylori infection, vascular complications of diabetes and as an inhibitor of certain carcinomas. Various methods were designed to improve its isolation from plant material, solubility, absorption and bioavailability. On the basis of recent studies, it is suggested that Scu could be a promising candidate for new natural drug and deserves particular attention in further research and development. |
| Databáze: | OpenAIRE |
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