Comparative genetics of hamster amylases
| Autor: | Wallace D. Dawson, Louise L. Huang |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Male
Genotype Hamster Biochemistry Salivary Glands Chinese hamster Cricetulus Species Specificity Inbred strain Cricetinae Genetics Animals Amylase Allele Pancreas Molecular Biology Gene Crosses Genetic Ecology Evolution Behavior and Systematics Polymorphism Genetic Mesocricetus biology Heterozygote advantage General Medicine biology.organism_classification Molecular biology Phenotype Amylases biology.protein Female |
| Zdroj: | Biochemical Genetics. 19:623-633 |
| ISSN: | 1573-4927 0006-2928 |
| DOI: | 10.1007/bf00483995 |
| Popis: | Syrian (Mesocricetus auratus) and Chinese (Cricetulus griseus) hamsters were phenotyped by electrophoresis for salivary and pancreatic amylases. Syrian hamsters possess two salivary amylase electromorphs, the more anodal (fast) being invariant in 250 outbred and 17 representatives of 5 highly inbred lines. The slow electromorph had activity equal to that of the fast amylase (heavy), or had distinctly less activity (light), or was absent (null). The slow electromorph is inherited as an autosomal semidominant trait with two alleles, Amy s and Amy o . Amy s homozygotes produce heavy, Amy o homozygotes null, and heterozygotes light phenotypes, respectively. Five inbred strains of hamsters were homozygous Amy o . Pancreatic amylase was monomorphic. Eight outbred Chinese hamsters showed no salivary amylase activity with electrophoresis, but slight activity with long incubation on starch-agar plates. However, pancreatic amylase activity in the Chinese hamster exceeded that in Syrian hamsters. Site duplication and apparent “null” alleles for amylase genes occur in muroid rodents. The evolutionary implications are discussed. |
| Databáze: | OpenAIRE |
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