Failure of a Glass Ionomer to Remineralize Apatite-depleted Dentin

Autor: Young Kyung Kim, F. R. Tay, S.K. Kim, Cky Yiu, D.H. Pashley, Lisha Gu, R.N. Weller, Jongryul Kim
Rok vydání: 2010
Předmět:
Zdroj: Journal of Dental Research. 89:230-235
ISSN: 1544-0591
0022-0345
DOI: 10.1177/0022034509357172
Popis: Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Human dentin specimens were acid-etched, bonded with Fuji IX GP, and immersed in a calcium-and-phosphate-containing 1.5X simulated body fluid (SBF) for 1-4 months. Polyacrylic acid and polyvinylphosphonic acid biomimetic analogs were added to the SBFs to create 2 additional remineralization media. Specimens were processed by transmission electron microscopy (TEM). No apatite deposition could be identified in the completely demineralized dentin in any of the specimens immersed in the 3 remineralization media, despite TEM/EDX evidence of diffusion of ions specific to the strontium-based GIC into the demineralized dentin. The hypothesis was rejected; mineral concentration alone is not a sufficient endpoint for assessing the success of contemporary remineralization strategies.
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Databáze: OpenAIRE