Altitude training induced alterations in erythrocyte rheological properties: A controlled comparison study in rats

Autor: Melek Bor-Kucukatay, Vural Kucukatay, Emine Kilic-Toprak, Rıdvan Çolak, Gülten Erken
Přispěvatelé: Tıp Fakültesi, 0-Belirlenecek
Rok vydání: 2014
Předmět:
erythrocyte deformability
Male
Erythrocyte Aggregation
Erythrocytes
Physiology
animal cell
altitude acclimatization
Erythrocyte aggregation
Rats
Sprague-Dawley
Random Allocation
treadmill exercise
Anoxia
Exercise performance
Medicine
Erythrocyte deformability
rat
animal
Treadmill
comparative study
training
exercise
Sprague Dawley rat
Altitude
Hematology
Animals
Athletic Performance
Disease Models
Animal
Erythrocyte Aggregation/*physiology
Erythrocytes/*physiology
Hypoxia/*blood
Physical Conditioning
Animal
Rats
Rheology/methods
Altitude training
Altitude Training
medicine.symptom
Rheology
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
flow kinetics
animal experiment
randomization
Article
blood
Physiology (medical)
controlled study
procedures
Exercise
nonhuman
hypoxia
business.industry
disease model
Hypoxia (medical)
RBC deformability
RBC Deformability
physiology
Comparison study
Physical therapy
erythrocyte
business
Zdroj: Clinical Hemorheology and Microcirculation. 58:479-488
ISSN: 1386-0291
DOI: 10.3233/ch-131711
Popis: Erken, Gülten (Balikesir Author)
Altitude training is frequently used by athletes to improve sea-level performance. However, the objective benefits of altitude training are controversial. This study aimed to investigate the possible alterations in hemorheological parameters in response to altitude training. Sprague Dawley rats, were divided into 6 groups: live low-train low (LLTL), live high-train high (LHTH), live high-train low (LHTL) and their controls live high and low (LHALC), live high (LHC), live low (LLC). LHC and LHTH groups were exposed to hypoxia (15% O-2, altitudes of 3000 m), 4 weeks. LHALC and LHTL were exposed to 12 hours hypoxia/normoxia per day, 4 weeks. Hypoxia was maintained by a hypoxic tent. The training protocol corresponded to 60-70% of maximal exercise capacity. Rats of training groups ran on treadmill for 20-30 min/day, 4 days/week, 4 weeks. Erythrocyte deformability of LHC group was increased compared to LHALC and LLC. Deformability of LHTH group was higher than LHALC and LLTL groups. No statistically significant alteration in erythrocyte aggregation parameters was observed. There were no significant relationships between RBC deformability and exercise performance. The results of this study show that, living (LHC) and training at altitude (LHTH) seems more advantageous in hemorheological point of view.
Pamukkale University Research Fund 2009BSP021
Databáze: OpenAIRE
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