MtDNA variation within local human populations in Bosnia and Herzegovina

Autor:	Naris Pojskić, Rifat Hadziselimovic, Gabrijela Radosavljevic, Damir Marjanović, Lejla Kapur-Pojskić
Rok vydání:	2014
Předmět:	Genetics education.field_of_study Mitochondrial DNA lcsh:QH426-470 HVS1 motif Population Haplotype Buccal swab Population genetics population structure Plant Science Biology Haplogroup Nucleotide diversity lcsh:Genetics haplogroups Genetic structure human mtDNA diversity education human activities
Zdroj:	Genetika, Vol 46, Iss 1, Pp 209-218 (2014)
ISSN:	1820-6069 0534-0012
Popis:	Being a crossroad of many ancient and recent historical migrations, Bosnia and Herzegovina (B&H) represents unique spot of multicultural and social diversity. The main aim of this study was to assess genetic structure of three local populations of mountain area from central part of B&H using mtDNA HVS-1 as an informative marker for population genetics studies. A 444 bp HVS-1 segment of control region of mtDNA extracted from buccal swabs was PCR amplified and sequenced. Haplotype and nucleotide diversity, average number of nucleotide differences, AMOVA and pairwise FST based on mtDNA haplotype and haplogroup frequencies were calculated. NJ tree was constructed based on pairwise FST results. Tajima?s D was calculated to evaluate population demographic status.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166e299a7c5548474101579906da469d https://doi.org/10.2298/gensr1401209k Zobrazit plný text záznamu Plný text ve formátu PDF