Aging Induces Changes in the Somatic Nerve and Postsynaptic Component without Any Alterations in Skeletal Muscles Morphology and Capacity to Carry Load of Wistar Rats
Autor: | Adriano Polican Ciena, Carlos Alberto Anaruma, Walter Krause Neto, Eliane Florencio Gama, Romeu Rodrigues de Souza, Wellington de Assis Silva |
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Přispěvatelé: | Univ Sao Judas Tadeu, Universidade Estadual Paulista (Unesp) |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Morphology (linguistics) Statistical difference frailty lcsh:RC321-571 sarcopenia 03 medical and health sciences 0302 clinical medicine Postsynaptic potential medicine Somatic nerve Tibial nerve lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Original Research Chemistry Compartment (ship) General Neuroscience neurodegeneration Anatomy medicine.disease 030104 developmental biology Sarcopenia Immunohistochemistry brain aging 030217 neurology & neurosurgery Neuroscience |
Zdroj: | Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Frontiers in Neuroscience, Vol 11 (2017) Frontiers in Neuroscience |
Popis: | Made available in DSpace on 2018-11-26T17:44:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-18 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) The present study aimed to analyze the morphology of the peripheral nerve, postsynaptic compartment, skeletal muscles and weight-bearing capacity of Wistar rats at specific ages. Twenty rats were divided into groups: 10 months-old (ADULT) and 24 months-old (OLD). After euthanasia, we prepared and analyzed the tibial nerve using transmission electron microscopy and the soleus and plantaris muscles for cytofluorescence and histochemistry. For the comparison of the results between groups we used dependent and independent Student's t-test with level of significance set at p |
Databáze: | OpenAIRE |
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