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| Autor: | Dana E. Orange, Caroline S. Jiang, Serene Z. Mirza, Salina Parveen, Ellen M. Gravallese, Tania Pannellini, Susan M. Goodman, Mayu O. Frank, Vivian P. Bykerk, Sarah L. Mackie, Mark P. Figgie, Nathalie E. Blachère, Edward F. DiCarlo, Ana Maria Orbai |
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| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Fibrin medicine.medical_specialty Neutrophils business.industry medicine.medical_treatment Immunology Morning stiffness medicine.disease Arthroplasty Arthritis Rheumatoid Rheumatology Internal medicine Rheumatoid arthritis medicine Humans Immunology and Allergy skin and connective tissue diseases business Morning |
| Zdroj: | Arthritis & Rheumatology. 73:175-176 |
| ISSN: | 2326-5205 2326-5191 |
| DOI: | 10.1002/art.41463 |
| Popis: | We are grateful for the interest in our manuscript describing synovial histology features that associate with patient reports of morning stiffness in rheumatoid arthritis1 . Jain et al raise an important point; not all joints in a patient with rheumatoid arthritis are affected equally at any given time, making it challenging to associate studies of synovium from only one joint with assessments of global patient symptoms. We had discovered that morning stiffness duration was associated with the presence of fibrin and neutrophils in synovium, however, neither of the questions used in this analysis focus on any particular joint and it is likely that joints other than the arthroplasty joint influenced patient responses. |
| Databáze: | OpenAIRE |
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