Au(I) Catalyzed HF Transfer: Tandem Alkyne Hydrofluorination and Perfluoroarene Functionalization

Autor:	Daniel Mulryan, Jack Rodwell, Nicholas A. Phillips, Mark R. Crimmin
Rok vydání:	2022
Předmět:	General Chemistry Catalysis
Zdroj:	ACS Catalysis. 12:3411-3419
ISSN:	2155-5435
DOI:	10.1021/acscatal.1c05474
Popis:	HF transfer reactions between organic substrates are potentially useful transformations. Such reactions require the development of catalytic systems that can promote both defluorination and fluorination steps in a single reaction sequence. Herein, we report a catalytic protocol in which an equivalent of HF is generated from a perfluoroarene | nucleophile pair and transferred directly to an alkyne. The reaction is catalyzed by [Au(IPr)N
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1654d450c39b37324cd28f801c07e5ae https://doi.org/10.1021/acscatal.1c05474 Zobrazit plný text záznamu