HBV vaccination status among healthcare workers: A cross-sectional study
| Autor: | Luigi Tonino Marsella, Daniela Feola, Giuseppe Signoriello, Nicola Coppola, Elpidio Maria Garzillo, AnnaRita Corvino, Monica Lamberti, Maria Grazia Lourdes Monaco, Antonio Arnese, Paola Arena |
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| Přispěvatelé: | Garzillo, E. M., Arnese, A., Coppola, N., Corvino, A., Feola, D., Monaco, M. G. L., Signoriello, G., Marsella, L. T., Arena, P., Lamberti, M. |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Cross-sectional study Hbv vaccination blood-borne viruses medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Environmental health Epidemiology Health care medicine 030212 general & internal medicine blood-borne viruse Advanced and Specialized Nursing Hepatitis B virus business.industry Health Policy Vaccination Public Health Environmental and Occupational Health virus diseases Original Articles Infectious Diseases Settore MED/42 epidemiology 030211 gastroenterology & hepatology business |
| Zdroj: | J Infect Prev |
| ISSN: | 1757-1782 1757-1774 |
| Popis: | Objective: The development of a vaccine against hepatitis B virus (HBV) is one of the improvements in strategy prevention during the last decades. Aim: To evaluate HBV-related vaccine status in healthcare workers (HCW) exposed to biological risk. Methods: The serum markers for HBV were collected from HCWs in two tertiary care hospitals in Naples (Italy). Multivariate statistical analysis was then performed to identify associated factors linked to the long-term immunogenicity of the HCWs. Results: All HBV vaccinated individuals were screened for whole marker patterns; all were HBsAg/anti-HBc negative. Of individuals, 20% had an anti-HB antibody titre < 10 IU/L. Multivariate statistical analysis highlighted that women were more protected than men (73.6% vs. 26.4%, P < 0.05). Additionally, nurses seem to maintain a higher antibody titre than doctors and other staff, such as auxiliary technicians ( P < 0.05). Conclusions: Our data support the evidence of a strong immunogenicity against HBV, assessed through the circulating antibody titre, when prophylactic vaccination is conducted in non-infantile age, particularly for women. The outcome of the study supports the central role of occupational physicians within the hospital districts in terms of primary prevention and maximum protection of HCWs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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