Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration
| Autor: | Oliver Reiser, Robert N. Grass, Thiwanka Samarakoon, Saqib Faisal, Toby R. Long, Ryan D. Kurtz, Alan Rolfe, Alexander Schätz, Wendelin J. Stark, Paul R. Hanson, Pradip K. Maity, Daniel L. Flynn |
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| Rok vydání: | 2010 |
| Předmět: |
inorganic chemicals
chemistry.chemical_classification Polymers organic chemicals Organic Chemistry Metal Nanoparticles Polymer Metathesis Biochemistry Combinatorial chemistry Article Catalysis Grubbs' catalyst Magnetics chemistry.chemical_compound Monomer chemistry Polymerization Reagent Organic chemistry heterocyclic compounds Mitsunobu reaction Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 13:8-10 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol1022382 |
| Popis: | A monomer-on-monomer (MoM) Mitsunobu reaction utilizing norbornenyl-tagged (Nb-tagged) reagents is reported, whereby purification was rapidly achieved by employing ring-opening metathesis polymerization, which was initiated by any of three methods utilizing Grubbs catalyst: (i) free catalyst in solution, (ii) surface-initiated catalyst-armed silica, or (iii) surface-initiated catalyst-armed Co/C magnetic nanoparticles. |
| Databáze: | OpenAIRE |
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