Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid

Autor: Chandana Das, Jarin Saktanasate, Carol L. Shields, Janet Manalac, Jerry A. Shields
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Pathology
genetic structures
melanocytosis
intra-arterial chemotherapy
lcsh:Ophthalmology
periocular chemotherapy
medicine.diagnostic_test
intravitreal chemotherapy
treatment
enhanced depth imaging
Choroid Neoplasms
enhanced depth imaging optical coherence tomography
eye
medicine.anatomical_structure
hemangioma
uveal melanoma
Tomography
Optical Coherence

nevus
medicine.medical_specialty
tumor
Ciliary body
monosomy 3
lymphoma
Drusen
Autoflouroscence
uvea
retinoblastoma
Hemangioma
Diagnosis
Differential

osteoma
Optical coherence tomography
medicine
melanoma
gene expression profiling
Nevus
Humans
metastasis
Chemotherapy
Osteoma
iris
Retinal pigment epithelium
Symposium
optical coherence tomography
intravenous chemotherapy
business.industry
Choroid
Subtenon′s chemotherapy
medicine.disease
Image Enhancement
Choroidal nevus
eye diseases
Ophthalmology
lcsh:RE1-994
sense organs
prognosis
business
malignancy
Zdroj: Indian Journal of Ophthalmology, Vol 63, Iss 2, Pp 117-121 (2015)
Indian Journal of Ophthalmology
ISSN: 1998-3689
0301-4738
Popis: Background: Spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT) can provide anatomic localization of intraocular tumors. Aims: The aim was to identify topographical and intrinsic patterns of choroidal tumors on EDI-OCT. Settings and Design: Retrospective review. Materials and Methods: Analysis of published reports and personal observations using office based EDI-OCT. Results: Using EDI-OCT, choroidal nevus displayed a smooth, dome-shaped topography with overlying retinal pigment epithelium alterations, drusen, and occasional subretinal cleft demonstrating photoreceptor loss. Small choroidal melanoma showed smooth, moderately dome-shaped topography, commonly with overlying shallow subretinal fluid that often depicted “shaggy” photoreceptors. Choroidal metastasis showed a minimally “lumpy, bumpy” surface topography and with overlying subretinal fluid and shaggy photoreceptors. Choroidal hemangioma showed a smooth, dome-shaped topography, with expansion of the affected small, medium, and large choroidal vessels. Choroidal lymphoma showed varying topography with increasing tumor thickness as “flat, rippled, or undulating (seasick)” surface. Choroidal osteoma displayed a smooth undulating surface with visible intralesional horizontal lines suggestive of bone lamellae and occasional horizontal and vertical tubules with intralesional “spongy” flecks. Choroidal melanocytosis appeared as uniformly thickened choroid with increased stromal density surrounding the normal choroidal vascular structures. Conclusions: Enhanced depth imaging-OCT can depict characteristic patterns that are suggestive of various choroidal tumors.
Databáze: OpenAIRE