Response to Role of Hyperleptinemia in the Regulation of Blood Pressure and Cardiac Function
| Autor: | Joaquim Pombo, Esna Uppal, Olena Rudyk, Clive W. Coen, Timothy South, James Clark, Anne-Maj Samuelsson, Sung Eun Bae, Lucilla Poston, Kathrine Redington, Paul D. Taylor, Michael J. Shattock |
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| Rok vydání: | 2014 |
| Předmět: |
Leptin
Male Cardiac function curve medicine.medical_specialty Nitric oxide chemistry.chemical_compound Pregnancy Internal medicine Internal Medicine medicine Animals Endothelial dysfunction business.industry Vascular disease Myocardium digestive oral and skin physiology Heart medicine.disease Endocrinology Blood pressure Adipose Tissue chemistry Prenatal Exposure Delayed Effects Hypertension Cardiology Female business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Hypertension. 63 |
| ISSN: | 1524-4563 0194-911X |
| DOI: | 10.1161/hypertensionaha.113.02399 |
| Popis: | We appreciate Dr Tsuda’s comments and observations on the involvement of nitric oxide in leptin-induced endothelial dysfunction and cardiac failure. We agree with Dr Tsuda that similar mechanisms might occur in neonatal leptin–treated rats. Because endothelial dysfunction represents an early form of vascular disease that precedes other cardiovascular complications, the role of neonatal leptin on endothelial function may provide valuable … |
| Databáze: | OpenAIRE |
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