Diagnostic accuracy of 128-slice dual-source CT coronary angiography: a randomized comparison of different acquisition protocols
| Autor: | Filippo Cademartiri, Stella L. Papadopoulou, Gabriel P. Krestin, Anoeshka S. Dharampal, Lisan A. Neefjes, Nico R. Mollet, Admir Dedic, Koen Nieman, Marcel van Straten, Tessa S. S. Genders, M. G. Myriam Hunink, Marcel L. Dijkshoorn, Alexia Rossi, Gert-Jan R. ten Kate, Pim J. de Feyter, Annick C. Weustink, Carl Schultz |
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| Přispěvatelé: | Radiology & Nuclear Medicine, Cardiology |
| Rok vydání: | 2013 |
| Předmět: |
Male
Coronary angiography medicine.medical_specialty CT coronary angiography Radiography Coronary Artery Disease Coronary Angiography Sensitivity and Specificity law.invention Radiography Dual-Energy Scanned Projection Coronary artery disease Randomized controlled trial Risk Factors law Heart rate Prevalence medicine Image quality Humans Radiology Nuclear Medicine and imaging Netherlands Neuroradiology Radiation dose medicine.diagnostic_test business.industry Incidence Ultrasound Reproducibility of Results Interventional radiology General Medicine Middle Aged medicine.disease Radiographic Image Interpretation Computer-Assisted Female Radiology Tomography X-Ray Computed business |
| Zdroj: | European Radiology, 23(3), 614-622. Springer-Verlag |
| ISSN: | 1432-1084 0938-7994 |
| Popis: | To compare the diagnostic performance and radiation exposure of 128-slice dual-source CT coronary angiography (CTCA) protocols to detect coronary stenosis with more than 50 % lumen obstruction. We prospectively included 459 symptomatic patients referred for CTCA. Patients were randomized between high-pitch spiral vs. narrow-window sequential CTCA protocols (heart rate below 65 bpm, group A), or between wide-window sequential vs. retrospective spiral protocols (heart rate above 65 bpm, group B). Diagnostic performance of CTCA was compared with quantitative coronary angiography in 267 patients. In group A (231 patients, 146 men, mean heart rate 58 ± 7 bpm), high-pitch spiral CTCA yielded a lower per-segment sensitivity compared to sequential CTCA (89 % vs. 97 %, P = 0.01). Specificity, PPV and NPV were comparable (95 %, 62 %, 99 % vs. 96 %, 73 %, 100 %, P > 0.05) but radiation dose was lower (1.16 ± 0.60 vs. 3.82 ± 1.65 mSv, P 0.05). Radiation dose of sequential CTCA was lower compared to retrospective CTCA (6.12 ± 2.58 vs. 8.13 ± 4.52 mSv, P |
| Databáze: | OpenAIRE |
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