Palliation of malignant dysphagia by laser therapy
| Autor: | A. P. Savage, H. Barr, R. J. Baigrie, R. A. Cobb, M. G. W. Kettlewell |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
medicine.medical_specialty Esophageal Neoplasms medicine.medical_treatment Adenocarcinoma Esophagus Recurrence Cause of Death medicine Carcinoma Humans Intubation Yttrium Treatment Failure Aged Aged 80 and over Neodymium Chemotherapy Esophageal Perforation Laser Coagulation business.industry Palliative Care Gastroenterology General Medicine Middle Aged medicine.disease Dysphagia Surgery Survival Rate Radiation therapy Treatment Outcome medicine.anatomical_structure Chemotherapy Adjuvant Carcinoma Squamous Cell Esophageal Stenosis Aluminum Silicates Radiotherapy Adjuvant medicine.symptom Deglutition Disorders Unresectable Esophageal Carcinoma business |
| Zdroj: | Diseases of the Esophagus. 10:243-246 |
| ISSN: | 1442-2050 1120-8694 |
| DOI: | 10.1093/dote/10.4.243 |
| Popis: | The outcome of 211 patients undergoing laser therapy as palliation for inoperable carcinoma of the esophagus is presented. The median age was 73 (range 44-97). The histology was adenocarcinoma for 127 patients and squamous-cell carcinoma for 84 patients. For 133 patients, laser was the only therapy while 56 patients had a combination of laser therapy and radiotherapy/chemotherapy. One patient underwent laser recanalization prior to resection while four patients had recurrence after resection treated by laser. Eleven patients underwent laser therapy for recurrent dysphagia after placement of an esophageal endoprosthesis. Eighteen patients died of procedure-related complications (i.e. 9% of patients and 2% of procedures). Of 32 procedures which perforated the tumour, 10 ended in death and the remaining patients were successfully treated conservatively. Good palliation was achieved for 170 patients (80%), while 19 patients underwent intubation after failure of laser therapy. Laser therapy failed to relieve dysphagia for 22 patients. The median survival was 20 weeks with the 1-year survival 12% and 2-year survival 4%; there were no significant differences in survival dependent on histology or administration of adjuvant radiotherapy or chemotherapy. Laser therapy provides a practical alternative to intubation in the treatment of malignant dysphagia for patients with unresectable esophageal carcinoma. |
| Databáze: | OpenAIRE |
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