Manufacturing of calcium phosphate scaffolds by pseudomorphic transformation of gypsum
| Autor: | Hudson de Araújo Batista, Miguel Ángel Rodríguez Barbero, R.G. Carrodéguas, Marcus Vinícius Lia Fook, Alexandre Sales Vasconcelos, Márcio José Batista Cardoso |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Hidroxiapatita carbonatada
Materials science Gypsum Mineralogy chemistry.chemical_element Pseudomorfismo 02 engineering and technology engineering.material Gypsum block Calcium 010402 general chemistry 01 natural sciences β-Fosfato tricálcico Industrial and Manufacturing Engineering lcsh:TP785-869 β-Tricalcium phosphate chemistry.chemical_compound Bone scaffold Bone regeneration Bone mineral Carbonated hydroxyapatite Yeso 021001 nanoscience & nanotechnology Phosphate Pseudomorphism 0104 chemical sciences Transformation (genetics) lcsh:Clay industries. Ceramics. Glass chemistry Chemical engineering Implante óseo Mechanics of Materials engineering Ceramics and Composites 0210 nano-technology |
| Zdroj: | Boletín de la Sociedad Española de Cerámica y Vidrio, Vol 55, Iss 3, Pp 105-113 (2016) |
| ISSN: | 0366-3175 |
| DOI: | 10.1016/j.bsecv.2016.02.003 |
| Popis: | Carbonated hydroxyapatite (CHAp) and β-tricalcium phosphate (β-TCP) have been employed for decades as constituents of scaffolds for bone regeneration because they chemically resemble bone mineral. In this study, the feasibility to manufacture CHAp/β-TCP scaffolds by pseudomorphic transformation of casted blocks of gypsum was investigated. The transformation was carried out by immersing the precursor gypsum block in 1 M (NH 4 ) 2 HPO 4 /1.33 M NH 4 OH solution with liquid/solid ratio of 10 mL/g and autoclaving at 120 °C and 203 kPa (2 atm) for 3 h at least. Neither shape nor dimensions significantly changed during transformation. The composition of scaffolds treated for 3 h was 70 wt.% CHAp and 30 wt.% β-TCP, and their compressive and diametral compressive strengths were 6.5 ± 0.7 and 5.3 ± 0.7 MPa, respectively. By increasing the time of treatment to 6 h, the composition of the scaffold enriched in β-TCP (60 wt.% CHAp and 40 wt.% β-TCP) but its compressive and diametral compressive strengths were not significantly affected (6.7 ± 0.9 and 5.4 ± 0.6 MPa, respectively). On the basis of the results obtained, it was concluded that this route is a good approach to the manufacturing of biphasic (CHAp/β-TCP) scaffolds from previously shaped pieces of gypsum. |
| Databáze: | OpenAIRE |
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