Production by Escherichia coli isolates of siderophore and other virulence factors and their pathogenic role in a cutaneous infection model

Autor: I. Kaleli, M. Demir
Rok vydání: 2004
Předmět:
Cutaneous infection model
Siderophore
siderophore
Siderophores
bacterial growth
medicine.disease_cause
Hydroxamic Acids
virulence factor
chemistry.chemical_compound
Mice
aerobactin
statistical significance
skin infection
Mice
Inbred BALB C
Virulence factors
biology
pathogenesis
article
General Medicine
Enterobacteriaceae
Infectious Diseases
priority journal
enterochelin
Urinary Tract Infections
Aerobactin
Microbiology (medical)
sampling
Virulence Factors
animal experiment
Virulence
animal tissue
Microbiology
Enterobactin
medicine
Escherichia coli
feces analysis
Animals
Humans
controlled study
human
mouse
nonhuman
animal model
bacterium isolate
control group
Skin Diseases
Bacterial
biology.organism_classification
Enterobactin/metabolism
Escherichia coli/growth & development/*pathogenicity
Hydroxamic Acids/metabolism
Siderophores/*biosynthesis
Skin Diseases
Bacterial/microbiology/*physiopathology
Urinary Tract Infections/microbiology/physiopathology
Virulence Factors/*biosynthesis
Virology
chemistry
bacteria
urinary tract infection
Bacteria
Zdroj: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 10(11)
ISSN: 1198-743X
Popis: Escherichia coli isolates from urinary tract infections (UTIs) (n = 124), extra-urinary sites (n = 37) and normal faecal samples (n = 51) were examined for the presence of virulence factors, including siderophores (aerobactin and enterobactin). The proportion of aerobactin producers was significantly higher in UTI (69.4%; p 0.001) and extra-urinary samples (70.3%; p 0.007) than in controls (41.2%), while the proportion of enterobactin producers was significantly lower in the UTI samples than in the controls (p 0.027). In a cutaneous infection model, aerobactin-positive E. coli showed more growth than non-aerobactin and non-enterobactin isolates, even when other virulence factors were identical. © 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases.
Databáze: OpenAIRE
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